PLTW Medical Detectives · Lesson 1 · Project

Diagnostic
Detectives

Project 1.5 — five patients walk into the clinic. You get their vital signs and physical exam. The case notes are blank. You ask the questions, you find the clues, you name the invader.

7 days · Plan the interview, interview your patient, narrow nine suspects, order the lab test, justify and treat, then present the case.
Tap any glowing word for the meaning in English and Spanish.

Do now · talk with a partner

What did the
1.4 doctor need?

In Activity 1.4 the physician found the answer with clues from three places. Name them from memory. Which one gave the most clues?

  • the physical exam — seen, heard, felt,
  • lab tests — measured,
  • and questions — what only the patient can tell you.

The twist this week: your patient's case notes are empty. Nobody asked the questions yet. You are the one who asks.

Project 1.5 · the case-file checklist

Eight steps to a diagnosis

This is the whole project on one card. Tap a step when your team finishes it — the card remembers.

Partners. Two detectives per patient. Both interview, both write, both sign the diagnosis.

How the case is graded · PLTW rubric, in our words

Three things the rubric looks for

CriteriaBasicProficientAdvanced
Interview questionsWorksheet 2 Questions are unclear, and they do not collect enough to solve the case. Questions are clear, but they still miss information the case needs. Questions are clear and planned to collect everything the case needs.
Case notesWorksheet 3 Notes describe only some of the evidence, and only partly. Notes describe some of the evidence completely. Notes describe all of the medical evidence, clearly.
Diagnosis with evidenceWorksheets 4–5 Diagnosis does not match the notes; little evidence. Diagnosis mostly matches the notes; a few pieces of evidence. Diagnosis clearly matches the notes; many pieces of evidence support it.

Aim for the green column. Every worksheet this week is built to get you there.

Collaboration · before the case starts

How will you two work together?

Real medical teams agree on rules before the patient arrives. Talk with your partner and tap the three rules you promise each other this week.

Write your three on Worksheet 1 — Meet Your Patient, Part A. On Day 6 the whole class will vote on its top five team norms.

Evidence · the medical file you were given
Your patient:

Physical exam · what the examiner found
    Case notes
    Empty — on purpose. Case notes come from the interview. Nobody has asked this patient a single question yet. By Day 3, this box is yours to fill.

    Write it down

    What you know —
    and what you don't

    On Worksheet 1 — Meet Your Patient: circle each vital sign as normal, too high, or too low for your patient's age, list the exam clues, and then the important part:

    • "We still need to find out ______." — at least four things.
    • "The exam clue that needs a question is ______, so we will ask ______."

    Detective's rule: a good detective writes down what they do NOT know. That list becomes tomorrow's questions.

    Before you leave

    Tomorrow: questions
    are your only tool

    No lab yet. No dictionary yet. Just you, a clipboard, and the questions you plan tonight in your head.

    Exit: tell your partner ONE thing you must ask your patient tomorrow.

    Day 2 · warm-up

    What is missing
    from your file?

    From memory, no worksheet: your patient's age, ONE vital sign that was off, ONE exam clue — and the biggest thing the file does not tell you.

    Today you turn "we don't know" into questions.

    The question toolbox

    Symptom questions and behavior questions

    Symptom questions ask what the body is doing. Behavior questions ask what the patient did, ate, drank, and where they went — the exposure. Sort each one, then check.

    Ask it well

    Tap the strong questions

    Three rules: an open question beats a yes/no question · ask one thing at a time · always follow up with "how long?" and "where exactly?"

    Worksheet 2

    Build your
    question list

    On Worksheet 2 — Plan the Interview, PLTW's interview template gives you the first questions. Copy the ones you need, then write three of your own for YOUR patient.

    • Look at the exam: white spots on the tonsils → ask about the throat. Ear infection → ask about the ears.
    • Look at the vitals: low blood pressure + fast pulse → ask about drinking, vomiting, bathroom.
    • Every patient gets the big four: travel · other people sick · unusual food or water · bug bites.

    "We will ask ______ because the file shows ______."

    Rehearse · five minutes each way

    Practice patient

    Partner A is the patient — read the card, answer only what is asked. Partner B is the detective — ask from Worksheet 2 and write every answer. Then swap.

    Detective: did your list get the sister? The sudden start? If not — what question was missing?

    Before you leave

    Your best
    question

    Pick the ONE question on your list that will do the most work tomorrow.

    "The best question we wrote is ______ because it will tell us ______."
    Hand it in with Worksheet 2.

    Day 3 · interview day

    Rules of the
    interview room

    • Introduce yourselves. "Hi, we're the detectives on your case."
    • One question at a time. Wait for the whole answer.
    • Write every answer — even "no." A "no" crosses off suspects.
    • Follow up. "How long?" "Where exactly?" "Who else?"
    • Thank your patient. They are helping you.

    The patient only answers what you ask. Nothing is volunteered. No question, no clue.

    Five patients · five stations

    How the stations work

    A patient actor sits at each station with the patient's answer card. Detective pairs go to their own patient only. Two rounds: ask everything on your list, huddle, then go back for what you missed.

    1stationGirl, age 9 · fever and a rash
    2stationBoy, age 3 · rash and a high fever
    3stationMan, age 33 · joint pain
    4stationWoman, age 25 · rash and fever
    5stationMan, age 44 · very sick stomach

    Actors: read your card, answer only what is asked, stay in character. Actor cards are in the teacher packet. If the room is small, the teacher can play all five patients, one station at a time.

    Interview · round 1

    Ask your
    questions

    Go to your patient's station. Ask every question on Worksheet 2 — Plan the Interview. Record each answer on Worksheet 3 — Interview & Case Notes, Part A.

    Start the clock (top right). When it runs out, come back to your seat even if you are not done — round 2 is for that.

    Between rounds

    Huddle

    Read your answers together. What did you learn? What is still missing? Which answer needs a follow-up — "how long?", "who else?", "what exactly did you drink?"

    Before round 2, write your follow-up questions in the Round 2 table at the bottom of Worksheet 3, page 1.

    Interview · round 2

    Follow-up
    questions

    Back to your patient. Ask the follow-ups. Detectives who ask "anything else you remember?" often get the clue that solves the case.

    Start the clock. Thank your patient when you leave.

    From answers to evidence

    Turn answers into case notes

    Rewrite the answers as short, clear sentences a different doctor could read — what · since when · what else · who else · where · food and drink. Tap each example for the model.

    Patient said"My throat hurts and it's hard to swallow. Maybe three days? And I've had a fever, like, four days."
    Case noteThroat pain and difficulty swallowing for 3 days. Fever for 4 days.
    Patient said"Two weeks ago I was in Central America visiting family. Nobody at home is sick, but a friend at school has been out with a sore throat."
    Case noteTraveled to Central America 2 weeks ago. No family members sick. A school friend has been out with a sore throat this week.
    Patient said"No cough. My eyes aren't red. Nothing hurts in my joints. My ears are fine."
    Case noteNO cough, NO red eyes, NO joint or muscle pain, NO ear pain. (Write the NO's — they cross suspects off.)
    Patient said"I drank water out of a stream on the hike. Oh — and I had a weird rash on my back, red circles with a red dot in the middle."
    Case noteDrank untreated stream water while hiking. Recalls a red bull's-eye rash on the lower back during the trip.
    Worksheet 3 · Part B

    Write the
    case notes

    On Worksheet 3 — Interview & Case Notes, Part B, write your patient's case notes in organized sentences. Use the frames — every box is a clue the rubric wants.

    • "Patient is a ______-year-old ______ who came in because ______."
    • "Symptoms: ______ for ______ days; ______ for ______ days."
    • "NO ______, NO ______, NO ______."
    • "Travel / contact / food and water: ______."

    Exit ticket: "The clue that surprised us was ______."

    Before you leave

    Nine suspects
    wait for you

    Tomorrow the Disease Dictionary comes out and the suspect board goes up. Bring your case notes — every NO you wrote is a suspect you can cross off.

    Hand in Worksheet 3 with your exit ticket.

    Day 4 · warm-up

    Three clues
    from memory

    No notes. Tell your partner the three clues from the interview that you think matter most — and ONE thing your patient does not have.

    Then open your case notes and check. Did memory keep the right ones?

    The diagnosis funnel

    Three questions, in order — for YOUR patient

    Question 1 · symptoms

    Do the symptoms match?

    Your case notes vs. the Symptoms of Disease column. The NO's are as powerful as the yeses.

    A rash + a sore throat with white spots is a different animal from a rash + a cough + red eyes.
    Question 2 · timing

    Does the incubation period fit?

    Count from the contact (trip, sick friend, bite, bad water) to the first symptoms.

    Sick 2 days after a 3-week trip? An illness with a 10–14 day incubation still fits — the contact was during the trip.
    Question 3 · spread

    Does the way it spreads fit?

    Transmission column: person-to-person, food or water, or a vector — a tick or mosquito bite.

    Woods and a bull's-eye rash → ticks. Tropical travel → mosquitoes. Broken water system → water.

    The lab can test for nine of the dictionary's sixteen suspects: Campylobacter, Cholera, E. coli, Lyme disease, Measles, Rotavirus, Salmonellosis, Strep/Scarlet fever, Zika. Those nine are on the board.

    Nine suspects · use the dictionary and YOUR case notes
    Board for:
    ✓ / ✗ in every box, then lock in:
    Suspect 1 · Symptoms match? 2 · Incubation fits? 3 · Spread fits? ✔ total
    Tap a suspect's name to read its Disease Dictionary card here.
    Worksheet 4 · C.E.R.

    Write it up

    On Worksheet 4 — Narrow the Suspects, fill the board for your patient, then write the diagnosis the way a detective does:

    • "We think Patient ___ has ______, caused by a ______ (bacterium / virus) called ______."
    • "The clues that fit are ______, ______, and ______."
    • "We crossed off ______ because ______."
    • "One thing we should still ask the patient is ______." — PLTW's rule: if you need more evidence, go back and get it.
    Step 8 · submit

    Submit your
    diagnosis

    Hand Worksheet 4 to the teacher with your diagnosis circled. Tomorrow the lab opens: you order the test for that agent, and your teacher hands you the result strip to read, with controls.

    If the result comes back negative, you go back to the clues. That is not failing — that is diagnosing.

    Day 5 · warm-up

    Two controls,
    one sentence each

    • A positive control is ______.
    • A negative control is ______.
    • If the two controls look the same, ______.

    Say them to your partner. Then the lab opens.

    The lab · order a test

    The test results are in

    Order one test at a time ($80 each). Your teacher hands you the result strip.

    Order for:

    Tests ordered: 0 · Lab bill: $0

    Worksheet 5 · Part A

    Justify the
    diagnosis

    The green column wants many pieces of evidence — three kinds. Worksheet 5 — Results & Treatment, Part B:

    • Claim: "Patient ___ has ______."
    • Evidence from the interview: "The patient told us ______ and ______."
    • Evidence from the exam and vitals: "The exam found ______."
    • Evidence from the lab: "The sample matched the ______ control for ______."
    • Reasoning: "These match the dictionary because ______, and we ruled out ______."

    Lab said negative? Record it, name the clue that sends you to a new suspect, and order again.

    Step 12 · consider the treatment

    Match each diagnosis to its treatment

    Use the Treatment column and what you know about agents: antibiotics kill bacteria; they do nothing to a virus. Some of the dictionary's treatment boxes are blank — that is your job.

    Reflect · Worksheet 5 Part C

    What was hard —
    and how you fixed it

    PLTW asks two questions. Answer both honestly:

    • "One challenge while diagnosing our patient was ______."
    • "We solved it by ______."

    "We guessed" is not a way to solve it. "We went back and asked the patient" is.

    Day 6 · warm-up

    One thing your
    partner did that helped

    Say it to them, out loud, specifically. "When you ______, it helped because ______."

    Then swap.

    Collaboration · reflect, then write

    How did the team work?

    1 · Helped
    What behaviors helped your team diagnose the patient?
    "It helped when we ______."
    2 · Got in the way
    What behaviors made it harder?
    "It was harder when ______."
    3 · Next time
    How could the team work better next time?
    "Next time we will ______."

    Discuss all three with your partner. Then write your own answers on Worksheet 6 — Team Norms & Real Life, Part A. No names, no blame — behaviors, not people.

    Team norms

    Write two or
    three rules

    Turn your reflection into rules for working in a team. A rule starts with "We will…" and describes something you can see or hear.

    • "We will listen to each other and not interrupt."
    • "We will value what each team member says."
    • "Each member of the team will be responsible for ______."

    Worksheet 6 Part A, bottom. Be ready to say your best rule to the class.

    Our team norms · class vote

    Pick the top five

    Share your rules; the teacher adds new ones. Hands up to vote, teacher tallies. The five with the most votes are our team norms for every group project from now on.

    Our team norms

    In real life

    Be your own self-advocate

    In this project you asked the questions. In real life you are the patient — and the best patients speak up, ask questions, and raise concerns. That is self-advocacy. A personal health journal makes it easy:

    Vital signsYour resting pulse, breathing, temperature — so you know YOUR normal.
    AllergiesFoods, medicines, bee stings. Anything that made you react.
    Illnesses & injuriesWhat, when, how long. A broken arm in 3rd grade counts.
    MedicinesNames, doses, why. Including vitamins and inhalers.
    Doctor visitsDate, who you saw, what they said, what to do next.
    Questions to askWrite them BEFORE the appointment. Nervous people forget.

    On Worksheet 6 — Team Norms & Real Life, Part B: start your journal with what you know today, and write three questions you would ask at your next check-up.

    Tomorrow · case reports

    The 60-second
    case frame

    Tomorrow each pair reports its case to the class in about a minute. Practice the frame with your partner now — each of you says half.

    • "Our patient was ______. The clue that mattered most was ______."
    • "We diagnosed ______ because ______. The lab said ______."
    • "The treatment is ______. If we were the doctor we would tell them ______."

    Exit ticket: write your half of the frame on the back of Worksheet 6.

    Day 7 · warm-up

    Case reports
    today

    Two minutes per pair, patients 1 through 5 in order. The audience listens with Worksheet 7 — Case Reports & Reflection, Part A: for every report, write the diagnosis and ONE clue that supported it.

    Audience rule: eyes on the presenters, pencil on the grid. Clap at the end, not the middle.

    Case reports · two minutes each
    2:00
    Now presentingPair 1
    Patient"Our patient was ______ (age, who)."
    Clue"The clue that mattered most was ______."
    Diagnosis"We diagnosed ______ because ______."
    Lab"The lab said ______ — the sample matched the ______ control."
    Treatment"The treatment is ______."
    Advice"We would tell the patient ______ so that ______."
    Medical Detectives · the unit problem

    Breaking news: Montgomery Hills

    Breaking news

    Reports are coming in from the town of Montgomery Hills: many residents are getting sick, and nobody knows why yet. Local doctors are asking for help.

    One patient was a case. A whole town is an outbreak. Talk with your partner: how would you use the skills from this lesson to figure out what is making everyone sick?

    • "First we would ask everyone ______, because ______."
    • "We would compare the sick people to the ______ people to find what they share."

    Worksheet 7 Part B. This question comes back in Lesson 2 — keep your answer.

    Lesson 1 reflection · Worksheet 7 Part C

    If you were
    the physician…

    What would you tell your patient about the disease agent that caused the illness — and how they could have prevented it?

    • "You have ______. It is caused by a ______ called ______."
    • "You most likely got it from ______."
    • "Next time, ______ so that ______."

    Claim, evidence, reasoning — and no scary words. The patient deserves to understand.

    Lesson 1 · closed

    What you can do now

    Measure vital signs. Design a fair test. Tell bacteria from viruses. Read a lab result with controls. Interview a patient, build a case file, and name the invader. In August you could do none of that.

    Next: Lesson 2 — the outbreak in Montgomery Hills.

    Word Bank · Banco de Palabras

    Every academic word in Medical Detectives so far. Tap one for the full card.

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